The FUS2 Anti-Human Antibody (clone AT2F4) from IBL- America is a Mouse Monoclonal antibody to N-alpha-acetyltransferase 80, NatH catalytic subunit, and NAA80. This antibody recognizes Homo Sapiens, and Human antigen. The FUS2 Anti-Human Antibody (clone AT2F4) has been validated for the following applications: EIA, Immunoassay, Cell Sorting, Isolation, ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
Vertebrate FUS2 genes, which are known to be putative tumor suppressor gene, contain several important domains such as the catalytic N-acetyltransferase (NAT) domain. NAT domain is essential enzymes involved in several sophisticated cellular processes such as N-acetylation, O-acetylatin. NAT enzymes may be involved in susceptibility to cancer including colorectal cancer because of the presence of carcinogenic heterocyclic amines in some cooked foods. FUS2 was physically localized to the cytoplasm. Also, FUS2 showed the actin dependent movement, closely related to the polarization in the budding yeast, Saccharomyces cerevisiae